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The Intestine Microbiome’s Connection to COVID-19
There may be rising proof that COVID-19 severity is influenced by our intestine microbiome. Those that have excessive ranges of useful, symbiotic micro organism of their guts are likely to have higher outcomes than those that have “dysbiosis” (unhealthy intestine microbiomes).
A research within the prestigious medical journal BMJ explores this additional:
Associations between intestine microbiota composition, ranges of cytokines and inflammatory markers in sufferers with COVID-19 recommend that the intestine microbiome is concerned within the magnitude of COVID-19 severity presumably through modulating host immune responses. Moreover, the intestine microbiota dysbiosis after illness decision might contribute to persistent signs, highlighting a necessity to know how intestine microorganisms are concerned in irritation and COVID-19.
Having a powerful microbiome seems to be key to avoiding a “cytokine storm” — a extreme immune response by which the physique releases too many cytokines into the blood too shortly. You may learn extra about that on this glorious opinion article printed in Frontiers in Immunology.
The intestine microbiota play an arterial position in sustaining immune homeostasis. The mucosal immune system, primarily the mucosa-associated lymphoid tissue similar to gut-associated lymphoid tissue (GALT) and bronchial-associated lymphoid tissue, is essential because it acts as the first line of protection in opposition to infections.
Now, what’s the No. 1 factor that disrupts our intestine microbiome? Antibiotics. Early on within the pandemic, 72% of all hospitalized COVID sufferers have been being handled with antibiotics. Many are nonetheless being handled with antibiotics, even though COVID is a viral illness. I think that the overuse of antibiotics is contributing to the COVID disaster.
I’ve studied the microbiome carefully for greater than 10 years, and I consider it’s a massively underappreciated think about our total well being.
That stated, I’m not a certified knowledgeable or physician. None of that is medical recommendation. However I’m consulting with docs and scientists to be taught extra about this.
I’ll hold readers up to date as I uncover extra about this vital subject. To be taught extra about why I feel startup buyers needs to be watching microbiome analysis, try this text I wrote final 12 months.
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